Amy Medlock, PhD
Professor of Interdisciplinary Biomedical Sciences in Biochemistry
Education
Postdoctoral Fellow, University of Cape Town, South Africa, 2003 – 2004
Postdoctoral Associate, University of Georgia Athens, Georgia, 2001 – 2003, 2004 – 2009
PhD, Biochemistry, University of Georgia Athens, Georgia, 2000
BS, Chemistry, Erskine College, 1994
Awards & Honors
Chair, Chemistry and Biology of Tetrapyrroles Gordon Research Conference, July 2022
Vice Chair, Chemistry and Biology of Tetrapyrroles Gordon Research Conference, July 2020
Discussion Leader, Chemistry and Biology of Tetrapyrroles Gordon Research Conference, July 2012 and 2016
Online Learning Fellow, University of Georgia, summer 2016
Outstanding Poster Presentation Award International Association of Medical Science Educators Annual Meeting June 2013
Southern Group on Educational Affairs 2013 Outstanding Poster Award for a professional educator April 2013
Areas of Expertise
Heme Biosynthesis
Heme Trafficking
Erythropoiesis
Biochemistry Education
Publications
The Mitochondrial Heme Metabolon: Insights into the Complex(ity) of Heme Synthesis and Distribution, R. B. Piel, III, H. A. Dailey, Jr. and A. E. Medlock, Molecular Genetics and Metabolism, 2019, pii: S1096-7192 (18), 30634-6.
Glutamine via α-ketoglutarate dehydrogenase provides succinyl-CoA for heme synthesis during erythropoiesis, J. S. Burch, J. R. Marcero, J. A. Maschek, J. E. Cox, L. K. Jackson, A. E. Medlock, J. D. Phillips, H. A. Dailey, Jr, Blood, 2018, 132 (10), 987-998.
Thoughts on interactions between PGRMC1 and diverse attested and potential hydrophobic ligands, M. A. Cahill and A. E. Medlock, Journal of Steroid Biochemistry and Molecular Biology, 2017, 171, 11-33.
*Heme Biosynthesis, A. E. Medlock and H.A. Dailey, chapter in Metalloprotein Active Site Assembly, 1st Ed., ed. Robert A. Scott and Michael K. Johnson, 2017, Wiley.
*A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase, R. B. Piel III, M. T. Shiferaw, A. A. Vashisht, J. Marcero, J. Praissman, J. Phillips, J. Wohlschlegel and A. E. Medlock, Biochemistry, 2016, 55 (37), 5204-5217.
*Identification of the Mitochondrial Heme Metabolism Complex, A. E. Medlock, M. T. Shiferaw, Jason R. Marcero, Ajay A. Vashisht, James A. Wohlschlegel, John D. Phillips, and Harry A. Dailey, PLoS One, 2015, 10(8):e0135896.
*Managing Micronutrient Nutrition: The Vitamin B12 Exemplar, A. Medlock, G. Crites , J. Stowe, MedEdPORTAL 2014. Available from:www.mededportal.org/publication/9771
Just-in-Time Teaching (JiTT): An Active Learning Pedagogy to Study Concepts in Cell Biology, V. T. Gaddy and A. E. Medlock, Med Sci Educ 2013, 23 (4), 664-665.
Mitochondrial Atpif1 regulates heme synthesis in developing erythroblasts, D. I. Shah, N. Takahashi-Makise, J. D. Cooney, L. Li, I. J. Schultz, E. L. Pierce, A. Narla, S. M. Hattangadi, A. E. Medlock, N. B. Langer, T. A. Dailey, S. N. Hurst, D. Faccenda, J. M. Wiwczar, S. K. Heggers, G. Vogin, W. Chen, C. Chen, D. R. Campagna, C. Brugnara, Y. Zhou, B. L. Elbert, N. N. Danial, M. D. Fleming, D. M. Ward, M. Campanella, , H. A. Dailey, J. Kaplan, and B. H. Paw, Nature 2012, 491(7425), 608-612.
*Identification and Characterization of Solvent-Filled Channels in Human Ferrochelatase, A. E. Medlock,W. Najahi-Missaoui, T. A. Ross, T. A. Dailey, J. Burch, J. R. O’Brien, W. N. Lanzilotta and H. A. Dailey, Biochemistry 2012, 51 (27), 5422-5433.